In this area of Hemophilia Village, you can learn about ReFacto Antihemophilic Factor (Recombinant) for people with hemophilia A.

Discover what ReFacto is and how it is made. Find out how ReFacto provides viral safety. And learn about the ReFacto R2 Kit, the first needle-less rapid reconstitution device for recombinant clotting factor with a prefilled diluent syringe.

While you're here, look into the way ReFacto works by replacing a missing component of healthy blood. You can also see how to use ReFacto to treat or prevent bleeding due to injury or surgery.

People with hemophilia A can try ReFacto before switching to it. Get details about the ReFacto Trial Prescription Program.

To learn more about ReFacto, you can also talk to your doctor.

Indication
ReFacto is indicated for the control and prevention of hemorrhagic episodes and for surgical prophylaxis and for short-term routine prophylaxis to reduce the frequency of spontaneous bleeding episodes in patients with hemophilia A. The effect of regular routine prophylaxis on long-term morbidity and mortality is unknown.

Important Safety Information

	•	As with the intravenous administration of any protein product, adverse reactions may include headache, fever, chills, flushing, nausea, vomiting, tiredness, or symptoms of allergic reactions.
	•	The remote possibility exists for hypersensitivity to non-human mammalian proteins. Known hypersensitivity to mouse or hamster proteins may be a contraindication to the use of ReFacto.
	•	Allergic reactions such as hives, itching, difficulty breathing, rapid heart rate, light-headedness and anaphylaxis have been reported for all factor VIII products. Patients should discontinue use of the product and contact their health care provider immediately and/or seek emergency care if any of these symptoms occur.

Please see ReFacto Prescribing Information

The health information contained herein is provided for educational purposes only and is not meant to replace personal discussions between health care providers and patients. All decisions about patient care must be made with a health care provider who can assess the special needs of each individual patient.